منابع مشابه
Acute Manic Relapse with Dexfenfluramine
TO THE EDITOR We read with interest the recent case report by Drs Soon-Jai Kwon et al. on Appetite Suppressor Induced Psychosis in which a case of de novo psychotic symptoms with phentermine use was reported. We had an Asian patient in whom dexfenfluramine, also an amphetamine related, centrally acting appetite suppressant, exacerbated an acute manic relapse. The patient is a 33 year old Asian ...
متن کاملDexfenfluramine protects against pulmonary hypertension in rats.
Dexfenfluramine (Dex), an appetite suppressant and serotonin reuptake inhibitor, is associated with pulmonary vascular disease (PVD) in some patients. The variability might be related to undetermined genetic abnormalities interacting with factors such as gender, weight loss, and vascular injury. We, therefore, assessed the effect of Dex (5 mg. kg(-1). day(-1)) in female obese rats, designated J...
متن کاملInhibition of delayed rectifier K+ channels by dexfenfluramine (Redux).
In light of recent reports linking K+ channel modulation with food intake and macronutrient preference, we investigated the effect of anorectic agent dexfenfluramine (d-FF), a 5-HT reuptake inhibitor and releasing agent, on the delayed rectifier K+ (DRK) channels in rat lingual taste cells using the patch-clamp technique in whole-cell configuration. In a concentration-dependent manner, d-FF cau...
متن کاملPrevalence and determinants of valvulopathy in patients treated with dexfenfluramine.
BACKGROUND Valve regurgitation has been associated with dexfenfluramine, but its prevalence and severity are uncertain. Additional factors that may contribute to valve regurgitation in patients exposed to this drug are poorly understood. METHODS AND RESULTS Echocardiography was performed on subjects recruited from 26 prescribing sites in 15 states. The total sample of 412 subjects included 17...
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ژورنال
عنوان ژورنال: British Journal of Psychiatry
سال: 1992
ISSN: 0007-1250,1472-1465
DOI: 10.1192/bjp.161.5.721b